One classic option for pointer location is mouse-trails, where a small footprint of the cursor shape will follow it around on screen. The mouse pointer size can be adjusted with this slider in the Accessibility system preferences. While you can eventually find your cursor by moving it around on the screen or bottoming-out its movement against a corner of the screen as a reference location, there are other options available in OS X to help prevent you from losing it in the first place. This might be especially true when using projectors and large-format displays, where the relatively small cursor can be difficult to locate. For example, if you need to dim your screen, it might be difficult to find the pointer and sometimes, optional pointers - such as those for text input or crosshairs - can become lost among the textures of images on the screen.

The default size of the mouse pointers in OS X should allow them to be viewable in most situations, but there could be some instances in which the cursor can be difficult to locate.